• CAMARADES Berlin LogoCAMARADES Systematic Review Wiki
  • 1 Welcome
  • 2 Preclinical Systematic Reviews
    • 2.1 What is a systematic review?
    • 2.2 What is a meta-analysis?
    • 2.3 Clinical & preclinical reviews
    • 2.4 Why perform preclinical SRs?
  • 3 Systematic Reviews & 3Rs
  • 4 Before You Start
    • 4.1 Is it necessary?
    • 4.2 Has it been done before?
    • 4.3 Is one already in progress?
    • 4.4 Build your systematic review team
      • 4.4.1 Collborating with your team
  • 5 Research Question
    • 5.1 Stakeholders
    • 5.2 Preclinical examples
  • 6 Protocol
    • 6.1 What is a protocol and why have one?
    • 6.2 Protocol templates
    • 6.3 Register your protocol
      • 6.3.1 Your protocol & 3Rs
  • 7 Systematic Search
    • 7.1 Selecting databases
      • 7.1.1 PubMed
      • 7.1.2 Embase
      • 7.1.3 Web of Science
      • 7.1.4 Other sources & grey literature
    • 7.2 Search strategy development
      • 7.2.1 Step 1: Find keywords and synonyms for each element
      • 7.2.2 Step 2: Index/subject terms (database-specific)
      • 7.2.3 Step 3: Combining search terms using Boolean operators
      • 7.2.4 Precision & sensitivity
      • 7.2.5 Tips & tricks
      • 7.2.6 Consulting an Information Specialist
    • 7.3 Combine search results
      • 7.3.1 Does the import order matter? YES!
    • 7.4 Deduplication
    • 7.5 Searching tools
    • 7.6 Find & retrieve full texts
      • 7.6.1 Tips & tricks for full text retrieval
  • 8 Study Selection
    • 8.1 Inclusion & exclusion criteria
    • 8.2 Apply your criteria
    • 8.3 Tools for screening
  • 9 Data Extraction
    • 9.1 Study characteristics
    • 9.2 Quantitative data
    • 9.3 Data extraction software
  • 10 Quality Assessment
    • 10.1 Why assess study quality?
    • 10.2 Reporting quality
    • 10.3 Risk of bias / methodological quality
    • 10.4 RoB assessment to inform analysis
  • 11 Meta-Analysis
    • 11.1 What is Meta-Analysis?
    • 11.2 Why perform Meta-Analysis?
    • 11.3 Meta-Analysis Tools
    • 11.4 Step 1. Calculate effect size
      • 11.4.1 Continuous
      • 11.4.2 Dichotomous Outcomes
      • 11.4.3 Median
      • 11.4.4 True number of Controls
    • 11.5 Step 2. Combine effect sizes
      • 11.5.1 Fixed Effects Model
      • 11.5.2 Random Effects Model
    • 11.6 Step 3. Investigate heterogeneity
    • 11.7 Step 4. Reporting biases
    • 11.8 Step 5. Interpret the results
  • 12 Tools for Systematic Review
  • 13 Publication
    • 13.1 Good reporting
  • 14 Resources & Links
    • 14.1 Systematic Review Facility - CAMARADES
    • 14.2 Templates & Guides
    • 14.3 GRADE Approach
  • 15 Workshops & Tutorials
    • 15.1 Workshops
    • 15.2 eLearning
    • 15.3 Meta-Analysis Tutorial
  • 16 About
    • 16.0.1 To cite the tool
    • 16.0.2 Our Team
  • Contact Us Here

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Preclinical Systematic Review Wiki

Section 14 Resources & Links

14.1 Systematic Review Facility - CAMARADES

  • SyRF
  • SyRF Help Guide

14.2 Templates & Guides

  • SYRCLE Protocol - Template & Paper
  • Borenstein et al., 2009. Introduction to Meta-Analysis
  • Vesterinen et al, 2014. “Meta-analysis of data from animal studies: a practical guide.” Journal of neuroscience methods
  • Cochrane Handbook
  • Cheat sheet: We have summarized the main points of our Introduction to SR workshop in this cheat sheet, including links to relevant references and resources.

14.3 GRADE Approach

  • Hooijmans et al., 2018. Preclinical GRADE Approach

Website by A Bannach-Brown on behalf of CAMARADES & CAMARADES Berlin

CAMARADES.Berlin@charite.de


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